Blood / Plasma Concentration Ratio Compared for Six Drugs in Blood from Six Normal Persons , Collected into Tubes Containing
نویسنده
چکیده
1624 CLINICALCHEMISTRY,Vol. 26, No. 11, 1980 Hospital, the mean urinary excretions (ig/24 h) as measured by this method were 34 for norepinephrine (range 9-84), 4 for epinephrine (range 0-24), and 252 for dopaniine (range 74-540), in good agreement with the results of Moyer et al. (1) for normal and hypertensive subjects. Isolation of the amines with the ionexchange columns takes about an hour; the chromatography requires 6 min per sample. All components of the assay procedure are commercially available without any special preparation, which makes it particularly suitable for use as a routine screening procedure.
منابع مشابه
Effect of various anticoagulants on the bioanalysis of drugs in rat blood: implication for pharmacokinetic studies of anticancer drugs
BACKGROUND Pharmacokinetic studies are vital in development and optimization of drugs. While blood samples can be collected either in EDTA, heparin or citrate containing tubes for the estimation of drug levels in plasma, EDTA tubes are more commonly used. The purpose of this study was to evaluate the effects of anticoagulants on bioanalysis of drugs. Six drugs used extensively in cancer therapy...
متن کاملEffects of storage times and temperatures on T3, T4, LH, prolactin, insulin, cortisol and progesterone concentrations in blood samples from cows.
Little is known about stability of hormones in blood samples stored under various conditions. This study was conducted to examine stability of triiodothyronine (T3), thyroxine (T4), luteinizing hormone (LH), prolactin, insulin, cortisol and progesterone in blood and serum samples. Experiment 1 was designed to determine if concentrations of these hormones were affected by exposure to cellular el...
متن کاملCytomegalovirus Active Infection in Persons Infected with Human Immunodeficiency Virus
Background and Objective: Cytomegalovirus (CMV), one of the most common opportunistic pathogens in patients infected with human immunodeficiency virus (HIV), can cause the diseases such as encephalitis, pneumonia, and chorioretinitis. This study aimed at molecular studying of CMV infection in individuals infected with the human immunodeficiency virus. Material and Methods: In this study, 50 ven...
متن کاملPERFORMANCE MODEL AND ANALYSIS OF BLOOD FLOW IN SMALL VESSELS WITH MAGNETIC EFFECTS
In this paper consider a two-fluid model consisting of a core region of suspension of all the erythrocytes (particles) in plasma (fluid) assumed to be a particle-fluid mixture and a peripheral layer of cell-free plasma (Newtonian fluid), has been proposed to represent blood flow in small diameter tubes with effects of magnetic. The analytical results obtained in the proposed model for effective...
متن کاملP-64: The Relationship between Polymorphism in Gene of Insulin-Like Growth Factor-I and The Serum Periparturient Concentration in Holstein Dairy Cows
Background: One of the most important metabolic factors affecting the reproductive activity is insulin-like growth factor-I (IGFI) concentration changes after calving. Recently, Maj et al. (2008) discovered a significant association between the IGF-I genotypes based on the 5'-untranslatedregion (5'-UTR) of IGF-I gene and the IGF-I blood level. The objective of this study is to investi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2004